The Fight Against Senescence + Peptides and Vaccines

This is the Sunday Newsletter sent to Subscribers on March 21, 2021. I post them on this blog from time to time. If you like it, become a Subscriber and it will show up in your inbox every Sunday.

Hey everyone, in this week’s Newsletter I’ve added two new sections:

  • Supplement of the Week, and
  • Your Weekly Dose of Inspiration.

These two join the intermittent appearances of News Worth Knowing and What’s Up, Covid?.

So, that said, here’s what’s in in this Newsletter:

Just scroll down and have at it.

News Worth Knowing Newsletter

These are the four recent news stories I’d like you to know about:

  1. Scientists and physicians are learning longevity medicine
  2. Anti-aging experts pinpoint the latest in anti-aging science
  3. Money is pouring in to fight senescent cells
  4. Can peptides make you younger

(1) Physicians and scientists join forces to develop the longevity medicine curriculum

Famed futurist Ray Kurweil got it right. Years ago he came up with the “three bridges” idea that forecasts a three-step process that will lead to extended lifespan. If interested, read my posts about Kurzweil’s theory, but suffice to say that the first bridge to cross has to do with what’s available now to extend healthspan and slow down the aging process.

The second bridge is what many serious physicians and scientists are working toward that may become available in a few short years, but to make that a reality they need to get on the same page, further their education and share their research.

One big step in that direction is the development of a new educational curriculum in longevity medicine. Read about that here.

(2) Can Science reverse Aging?

Well, as indicated above, those busy beaver scientists are well on their way to doing just that. Check out this BBC video that features scientists Professor Linda Partridge, Dr. David Sinclair, Mark Allen, MD. and biohacker Dave Asprey who address slowing down the aging process via:

I encourage you to click the above links that will take you to an assortment of posts that can help you.

(3) A Senescence-reversing Start-up Lands £1.3 Million ($1.8 million) In Funding

If you’ve been a Subscriber for a while, it’s no surprise to you that one of my major anti-aging focal points is on senescent cells; specifically, reducing their number.

I’m not the only one!

Led by scientists like Drs. Judith Campisi, Julie Anderson and Martin Brand, The Buck Institute has devoted much money and resources in senescence research, and for good reason.

As I outline in Can 4 Natural Compounds “Eliminate Senescent Cells” and Prolong Your Healthy Lifespan? and Can New Senolytics Drugs Delay Aging?:

  • Cellular senescence is a major cause of aging and the various chronic diseases that accompany it.
  • Specific “senolytic agents” (think drugs and supplements) have proven their ability to alleviate multiple characteristics associated with aging. It may eventually become feasible to delay, prevent, alleviate or even reverse multiple chronic diseases and disabilities as a group, instead of just one at a time.

Given this as context, you can understand why the company SENISCA received about $1.8 million for the development of “senotherapeutic interventions” that target both disease-causing and aesthetic aspects of aging. Read about it here.

(4) Can Peptides Make You Younger?

To find out, watch Ben Greenfield’s interview of Dr. William Seeds, a medical doctor board certified in orthopedic surgery, sports medicine, anti-aging, and regenerative medicine who has become a leading researcher and educator in the field of peptides.

Peptides are short chains of between two and fifty amino acids, linked by peptide bonds. I’ve long been interested in them because some have clear anti-aging-type benefits. But I have yet to write about them, because a lay person can not buy them, and they can be dangerous to use if you don’t know what you’re doing.

Nonetheless, peptides are exciting to contemplate for anti-aging, growth hormone, deep sleep, hair loss, enhanced cognition, and more — all of which you may learn about on Ben’s podcast with Dr. Seeds.

Supplement of the Week: Vitamin D Newsletter

So much has been written about Vitamin D that I hesitated to showcase it as the Supplement of the Week, as it does seem over-hyped as some “do-it-all” supplement. Nonetheless, given that cancer is the number two killer in the USA and in much of the industrialized world (behind heart disease), I want to bring your attention to a recent study, a summary of which was published by Harvard Health.

Of the more than 25,000 men and women who were randomly assigned to take 2,000 international units (IU) of vitamin D daily for an average of 5.3 years, nearly 20% were less likely to have an advanced cancer than those who received a placebo. (“Advanced cancer” is defined here as one that metastasized — spread from the original tumor site — or proved fatal.)

Those of normal weight experienced a 38% decrease, which highlights yet another reason to win the battle of the bulge.

Currently, the highest rated Vitamin D on Amazon is Pure Encapsulations Vitamin D3.

Your Weekly Dose of Inspiration

Ki Hong, 93 years young

Let Ki Hong inspire you!

Ki Hong is 93 years young. Her secret — walking.

Here’s what she has to say about it:

Exercising and moving around is very important to me. It has been my whole life. When I was younger, I liked to ice skate, bike ride, and hike. I’ve always believed that it’s really important to move around to keep your body strong. Now, as a 93-year-old grandmother, I can confidently say that you can get through anything if you have your health, but you can lose everything if you lose your health.

Read her story here.

What’s Up, Covid? Newsletter

I want to tell you about:

  • The three vaccines available in the USA
  • A nasal spray that helps prevent Covid infection
  • The vulnerability of being overweight and over 60

The Three Vaccines Available in the USA

Which vaccine should I get?

Doesn’t matter.

Watch what Dr. Peter Chin-Hong says on the matter, which distills down to: The Johnson & Johnson, Pfizer and Moderna vaccines are all equally effective at preventing severe disease and death.

Don’t intend to get vaccinated?

Then you need a plan. At minimum, begin with Xlear.

Xlear Helps Prevent Covid

Elisa Song, MD holding a bottle of Xlear

That pic above is of Dr. Elisa Song. Over the last year, she has specialized in preventing and treating Covid, particularly in children, given that she’s a Pediatrician.

What she’s holding is a nasal spray called Xlear. Regular readers know about Xlear, because for many months now I’ve touted its effectiveness in helping to prevent Covid infections. I won’t repeat the case for Xlear, but if interested you can read my post,  Can An Inhaled Nasal Spray Kill Covid?.

Frankly, I feel vindicated that a physician with the stature of Dr. Song agrees, but I’m not telling you this to high five myself, but to provide you a weapon in your arsenal against Covid if you — or someone you know — does not intend to get vaccinated.

Or if you have months to wait for your turn to get vaccinated.

Xlear is by no means as effective as a vaccine, but it’s a whole lot better than nothing.

And I would be remiss if I did not mention that if you, or anybody you know, does not intend to get vaccinated, you need a plan to not get infected, but if infected, to minimize the severity of symptoms, especially over the long haul. Click here to see how I can help.

One important wake-up call we got from the pandemic is how vitally important it is to improve the personal health of many of us, particularly our size.

The Vulnerability of Being Overweight and Over 60

According to the CDC, 42% of adults in the USA are obese and 70% are overweight. In the World Health Organization’s European Region, about 20% of men and 23% of women are obese, and more than 50% are overweight.

As New York Times Personal Health columnist Jane Brody reports, after old age, obesity is the second leading risk factor for death among those who become infected and critically ill with Covid-19. Two other major risks for Covid, Type 2 diabetes and high blood pressure, are most often the result of excess weight, which in turn reflects unhealthy dietary and exercise habits.

If all that doesn’t give you indigestion, CNBC reports that the protection offered to Covid infection subsequent to a prior infection is not as robust as first thought.

While prior infection gave those under the age of 65 around 80% protection against reinfection, for people aged 65 and older it conferred only 47% protection, indicating that they are more likely to catch Covid-19 again.

The moral of this story for those who will not get vaccinated is that if you’re older and/or overweight, even if you survive a first infection, you have a good chance of getting it again.

You Need A Plan!



Last Updated on February 28, 2022 by Joe Garma

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Joe Garma

I help people live with more vitality and strength. I'm a big believer in sustainability, and am a bit nutty about optimizing my diet, supplements, hormones and exercise. To get exclusive Updates, tips and be on your way to a stronger, more youthful body, join my weekly Newsletter. You can also find me on LinkedIn, Twitter and Instagram.

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